Improvements on Retrosynthetic Analysis

Success in organic chemistry is heavily reliant on a student’s ability to identify patterns. Until recently, I organized my course by functional group. It was only after I adopted Joel Karty’s approach that I recognized that the variety of reactions used to synthesize each functional group can vary widely and that this variance makes it … Continue reading Improvements on Retrosynthetic Analysis

Reasoning By Analogy

For twelve years I’ve taught organic chemistry to a mixture of chemistry and biology students. I always begin Organic I by asking my students this same question: Why are you taking this class? Some students respond that the curriculum plan for their major or career requires the organic chemistry course sequence. For other students, organic … Continue reading Reasoning By Analogy

Three Lessons from Student Exams

The advantages of Joel’s approach surfaced in the second semester of the first year I taught a mechanistically organized course while using Joel’s manuscript instead of a traditional textbook. Student experience on exams demonstrated to me three points: I had unwittingly expected students to memorize organic chemistry instead of think mechanistically; the focus on mechanisms … Continue reading Three Lessons from Student Exams

The Benefits of a Mechanistically Organized Book When Teaching a 2-cycle Approach

Two-cycle organic chemistry is a pedagogical approach that has gained in popularity over the last couple decades. It’s a rather simple idea: The first semester course is treated as something of a survey, dealing primarily with the fundamentals, whereas the second semester revisits many of the same topics from the first semester, but treating them … Continue reading The Benefits of a Mechanistically Organized Book When Teaching a 2-cycle Approach

Predicting the Products of an SN1/SN2/E1/E2 Competition

When I teach nucleophilic substitution and elimination reactions, I find that students typically have very little trouble drawing each mechanism and predicting the products, so long as they are specifically told which reaction. But many students find one aspect very challenging: predicting the winner of an SN1/SN2/E1/E2 competition. In my first few years of teaching, … Continue reading Predicting the Products of an SN1/SN2/E1/E2 Competition

What About Nonmajors and Pre-health Students?

I am convinced that students learn organic chemistry best when we teach them how to work with mechanisms prior to delving into predicting products and devising syntheses. And when dealing with reactions, it is important to organize reactions according to mechanism, in order for students to have a sustained focus on mechanisms throughout the year.  … Continue reading What About Nonmajors and Pre-health Students?