Ah yes, it is that time of year again; a seven week coast to the Organic Chemistry II finish line. All the elementary steps have been introduced and discussed multiple times and it feels like review from here. Most texts seem to end with reactions like Aldol condensation and Robinson Annulation. A functional group approach … Continue reading All Downhill After the Aldol
There were two places in Joel’s text that surprised me: where 1,2 versus 1,4 addition to a conjugated diene appeared—Chapter 11—and where direct versus conjugate nucleophilic addition to polar pi bonds appeared—Chapter 17. Both of these chapters introduce basic concepts and then expand all the way to complex applications, much further than a functional-group organized … Continue reading When to Introduce Conjugate Addition: Sometimes More is More
As a new professor, I had mixed feelings about spring break. On the one hand, I was so ready for a vacation, but on the other, I remembered what it was like as a student that time of year. Your mind is on anything but classes. Not only are you looking forward to a week … Continue reading Do Your Students “Get” Aldol Reactions?
I gave my second exam of the semester a few days ago. One of the questions presented students with the reactants, conditions, and product of a Robinson annulation reaction. The question was worded: “Draw the complete, detailed mechanism for the following Robinson annulation.” After I collected the exams, I returned to my office to find … Continue reading A Reaction by Any Other Name…